Figure 1. Differentially expressed circRNAs in NSCLC. The differentially expressed circRNAs between NSCLC tissues and adjacent normal tissues in (A) GSE101586 or (B) GSE112214 were assessed using principal component analysis and a volcano plot. Red indicates high expression while blue indicates low expression. (C) Among the differentially expressed circRNAs in GSE101586, 18 were downregulated and 107 were upregulated in NSCLC tissues. In GSE112214, 423 circRNAs were downregulated and 319 were upregulated in NSCLC tissues. (D) The overlapping differentially expressed circRNAs between GSE101586 and GSE112214 were analyzed.