Research Paper Volume 12, Issue 14 pp 14355—14364

LncRNA FGD5-AS1 promotes tumor growth by regulating MCL1 via sponging miR-153-3p in oral cancer

Figure 2. Knockdown of FGD5-AS1 inhibits proliferation, migration and invasion in SCC4 cells. (A) The expression of FGD5-AS1 in SCC4 cells after FGD5-AS1 si-RNA or si-Scramble transfection was determined by qRT-PCR (*p<0.05). (B) CKK-8 assay was used to examine the cell growth at 0, 24, 48 and 72 h (*p<0.05). (C) Edu assay was used to calculated cell proliferation (*p<0.05). (D) Wound healing assay was used to detect cell migration (*p<0.05). (E) Transwell assay was performed to check cell invasive ability (*p<0.05).