Research Paper Volume 12, Issue 14 pp 14355—14364

LncRNA FGD5-AS1 promotes tumor growth by regulating MCL1 via sponging miR-153-3p in oral cancer

Figure 6. LncRNA FGD5-AS1 promotes OC progression via miR-153-3p/MCL1 axis. (A) FGD5-AS1 plasmid was transfected into SCC4 cells, and qRT-PCR analysis was used to detect the transfection efficiency (*p<0.05). miR-153-3p or si-MCL1 was cotransfected into SCC4 cells with FGD5-AS1 plasmid. CCK8 assay (B) and Edu assay (C) was used to calculate cell proliferation (*p<0.05 vs pcDNA3.1, #p<0.05 vs FGD5-AS1). (D) Wound healing assay was used to detect cell migration (*p<0.05 vs pcDNA3.1, #p<0.05 vs FGD5-AS1). (E) Transwell assay was performed to check cell invasive ability (*p<0.05 vs pcDNA3.1, #p<0.05 vs FGD5-AS1).