Research Paper Volume 12, Issue 14 pp 14452—14466

Long noncoding RNA LINC01559 promotes pancreatic cancer progression by acting as a competing endogenous RNA of miR-1343-3p to upregulate RAF1 expression

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Figure 3.

Silence of LINC01559 expression suppressed PC cell migration and invasion. (AD) The effect of LINC01559 expression on migration and invasion of PC cells by using transwell assay (200×) (bar: 50 μm). (EG) Wound healing assay demonstrates the suppressed migration ability of shlinc01559 compared to shCtrl in PANC-1 and MIA PaCa-2 cell lines (200×) (bar: 50 μm). (H) Western blotting was used to detect MMP2 and MMP9 in PC cells, which were indexs for migration ability and were reported in previous studies.*p < 0.05, **p < 0.01, ***p < 0.001