Research Paper Volume 12, Issue 14 pp 14452—14466

Long noncoding RNA LINC01559 promotes pancreatic cancer progression by acting as a competing endogenous RNA of miR-1343-3p to upregulate RAF1 expression

Figure 3. Silence of LINC01559 expression suppressed PC cell migration and invasion. (AD) The effect of LINC01559 expression on migration and invasion of PC cells by using transwell assay (200×) (bar: 50 μm). (EG) Wound healing assay demonstrates the suppressed migration ability of shlinc01559 compared to shCtrl in PANC-1 and MIA PaCa-2 cell lines (200×) (bar: 50 μm). (H) Western blotting was used to detect MMP2 and MMP9 in PC cells, which were indexs for migration ability and were reported in previous studies.*p < 0.05, **p < 0.01, ***p < 0.001