Research Paper Volume 12, Issue 14 pp 14480—14489

MiR-135a inhibits non-small cell lung cancer progression by suppressing RAB1B expression and the RAS pathway

Figure 3. MiR-135a inhibits the expression of multiple components of the RAS pathway. (A, B) Overexpression of RAB1B antagonized the effects of miR-135a mimics on (A) cell viability and (B) colony forming ability. (C, D) Western blotting analysis of the RAB1B and RAS pathway components in (C) A549 and (D) H1299 cells transduced with miR-135a mimics. Due to the overall contrast adjustment, some parts are no background in figure 3C and 3D.