Research Paper Volume 12, Issue 14 pp 14480—14489

MiR-135a inhibits non-small cell lung cancer progression by suppressing RAB1B expression and the RAS pathway

Figure 5. Effects of downregulation of miR-135a on RAB1B and the RAS signaling pathway in NSCLC cell progression. Downregulation of miR-135a increased the expression of downstream target gene RAB1B and RAS pathway members, thereby promoting proliferation and invasion/metastasis of NSCLC.