Figure 2. Identifying differentially expressed genes between CDCA5-high and -low patients. (A) Volcano plot of differential gene profiles between CDCA5-high and -low groups. (B) KEGG pathway analysis by GSEA shows that genes involved in cell proliferation, DNA replication and p53 pathway are enriched in CDCA5-high patients. Venn plot demonstrates the overlapping between differentially expressed genes and genes participating in different biological processes. Each circle in the Venn plot represents one set and the number in the overlaid area represents the common genes between the sets. (C) GSEA enrichment plots demonstrated gene enrichment results from Figure 3B.