Research Paper Advance Articles

Targeting CCL20 inhibits subarachnoid hemorrhage-related neuroinflammation in mice

Figure 4. The effects of CCL20 on the neuronal apoptosis and microglial activation after SAH. (A) Neuronal apoptosis was determined by coimmunofluorescence staining for TUNEL (red), NeuN (green) and DAPI (blue) in the right temporal cerebral cortex at 24 h after SAH (n = 5 per group). Scale bar = 50 μm. (B) Microglial activation was detected through coimmunofluorescence staining for Iba1 (red) and DAPI (blue) in the cerebral cortical at 24 h after SAH (n = 5 per group). Scale bar = 50 μm. Data were presented as mean ± SD. **P < 0.01 vs. the sham group. ##P < 0.01 vs. the SAH+IgG group.