Research Paper Volume 12, Issue 14 pp 14885—14896

Circular RNA DHX33 promotes malignant behavior in ccRCC by targeting miR-489-3p/MEK1 axis

Figure 1. Screening of ccRCC-related circRNAs in GSE137836 dataset. (A, B) Hierarchical clustering analysis and volcano plots of significantly differentially expressed circRNAs in ccRCC tissues from the GSE137836 dataset. (C) GO enrichment analysis for dysregulated circRNAs gene symbols. (D) 5 upregulated circRNAs in 8 paired ccRCC tissues was determined by using RT-qPCR. *p<0.05, **p<0.01.