Research Paper Volume 12, Issue 14 pp 14885—14896

Circular RNA DHX33 promotes malignant behavior in ccRCC by targeting miR-489-3p/MEK1 axis

Figure 2. circDHX33 was highly expressed in ccRCC. (A) Schematic diagram of circDHX33. (B) Random hexamer or oligo (dT)18 primers were used in the reverse transcription experiments. (C) The relative RNA levels were determined by qRT-PCR. (D) The expression of circDHX33 in 47 paired ccRCC tissues was detected by qRT-PCR. (E, F) High circDHX33 expression was linked to advanced TNM stage and metastasis in ccRCC patients. *p<0.05, **p<0.01.