Research Paper Volume 12, Issue 14 pp 14966—14977

MiR-155 contributes to intestinal barrier dysfunction in DSS-induced mice colitis via targeting HIF-1α/TFF-3 axis

Figure 1. MiR-155 antagomir reduced miR-155 level in DSS-induced colitis. (A) The schema of the animal experiment. (B) Location of miR-155 antagomir in mouse colon. Red marked by green arrows was positive signal (magnification ×20). (C) QRT-PCR analysis of miR-155 level in mice colonic tissue. Each bar represents mean ± SD, n=8 from each group. #P > 0.05, **P < 0.01 vs. DSS group. (D) In situ hybridization analysis of miR-155 in mice colon. Green marked by red arrows was positive signal for miR-155 (magnification ×200).