Research Paper Volume 12, Issue 14 pp 14966—14977

MiR-155 contributes to intestinal barrier dysfunction in DSS-induced mice colitis via targeting HIF-1α/TFF-3 axis

Figure 3. Histopathological evaluation of intestinal inflammation in all groups. (A) Hematoxylin and eosin (HE) and Periodic Acid-Schiff (PAS) analysis of colon specimens (magnification ×100). Massive inflammation cell infiltration, mucosal erosion, and submucosa edema were observed throughout the colons in the DSS and ant-NC group. For PAS stain, red particles marked by black arrows represented the positive change. (B) Histological inflammation scores in all groups were presented. (C) PAS+ cells per high power field in all groups were presented. Each bar represents mean ± SD, n=5 from each group. #P > 0.05, *P < 0.05, **P < 0.01 vs. DSS group.