Research Paper Volume 12, Issue 14 pp 15037—15049

2-methylbenzoyl berbamine, a multi-targeted inhibitor, suppresses the growth of human osteosarcoma through disabling NF-κB, ERK and AKT signaling networks

Figure 4. BBD24 suppressed OS cells migration and invasion. 1×105 MG63 and HOS cells were seeded on a transwell insert, then treating with different concentrations of BBD24. (AC) BBD24 reduced the migration and invasion of MG63 and HOS cells in a dose dependent manner. Results were expressed as means ± SD of three independent experiments. * P<0.05.