Research Paper Volume 12, Issue 18 pp 18019—18032

Long non-coding RNA AGAP2-AS1 increases the invasiveness of papillary thyroid cancer

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Figure 2. Knockdown of AGAP2-AS1 inhibits invasion and migration in PTC cells. (A) RT-PCR of AGAP2-AS1 after si-RNA suppression in PTC cells; **P < 0.01 vs. NC. (B) Transwell assay in PTC cells after transfection with si-AGAP2-AS1 or NC. Data are presented as the mean ± SD, analyzed using independent samples t-test. **P < 0.01 vs. NC. (C, D) Wound healing assay in PTC cells after transfection with si-AGAP2-AS1 or NC. E. Western analysis of N-cadherin, E-cadherin, MMP2, MMP9, and Vimentin after transfection with si-AGAP2-AS1 or NC in PTC cells; **P < 0.01, *P < 0.05 vs. NC.