Research Paper Volume 12, Issue 16 pp 16111—16125

Testosterone ameliorates vascular aging via the Gas6/Axl signaling pathway

Figure 3. The role of testosterone and Gas6/Axl in structural changes of aging vessel. (A) Carotid artery (CA) and abdominal aorta (AA) of ultrasonography. (B) Intima-media thickness (IMT) of carotid artery. (C) Systolic diameter (Ds) and diastolic diameter (Dd) of carotid artery. (D) Coefficient distention (CD) of carotid artery. (E) IMT of abdominal aorta. (F) Ds and Dd of abdominal aorta. (G) CD of abdominal aorta. Data are mean ± SD; *P < 0.05, **P < 0.01 and ***P < 0.001 vs. WT young group; P < 0.05 vs. WT old group; &P < 0.05, &&P < 0.01 and &&&P < 0.001 vs. Axl-/- young group; #P<0.05 vs. Axl-/- old group; n = 8 for each group.