Research Paper Volume 12, Issue 16 pp 16111—16125

Testosterone ameliorates vascular aging via the Gas6/Axl signaling pathway

Figure 4. The role of testosterone and Gas6/Axl in vascular stiffness and blood pressure of aging vessel. (A) Stiffness parameter (β). (B) Pressure-strain elastic modulus (Ep). (C) Distensibility coefficient (DC). (D) Compliance coefficient (CC). (E) Systolic pressure (SBP) and diastolic blood pressure (DSP). (F) Mean arterial pressure (MAP). (G) Pulse pressure (PP). Data are mean ± SD; *P < 0.05, **P < 0.01 and ***P < 0.001 vs. WT young group; P < 0.05 and ††P < 0.01 vs. WT old group; &P < 0.05, &&P < 0.01 and &&&P < 0.001 vs. Axl-/- young group; #P<0.05 vs. Axl-/- old group; n = 8 for each group.