Research Paper Advance Articles

Sirt1 improves heart failure through modulating the NF-κB p65/microRNA-155/BNDF signaling cascade

Effects of miR-155 inhibition on cardiomyocyte apoptosis. (A) Expression of miR-155; (B) Cell viability determined by MTT assay; (C) Cell apoptosis determined by flow cytometry; (D) Protein expression of apoptosis-related factors; *p

Figure 4. Effects of miR-155 inhibition on cardiomyocyte apoptosis. (A) Expression of miR-155; (B) Cell viability determined by MTT assay; (C) Cell apoptosis determined by flow cytometry; (D) Protein expression of apoptosis-related factors; *p < 0.05 vs. control group or model + inhibitor NC. Data were expressed as a mean ± standard deviation. Three or more groups were analyzed by one-way analysis of variance (ANOVA) and Tukey's post hoc test. Data comparison between different time points was performed by repeated measures ANOVA and Bonferroni post hoc test. The cell experiment was repeated three times.