Research Paper Volume 12, Issue 16 pp 16294—16303

Circulating exosomal miR-144-3p inhibits the mobilization of endothelial progenitor cells post myocardial infarction via regulating the MMP9 pathway

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Figure 7.

The schematic illustration of proposed mechanism. Exosomal miR-144-3p disturbed the MMP-9 pathway by inhibiting Ets1 expression in MSCs, and subsequently impaired the mobilization of EPCs from bone marrow microenvironment.