Research Paper Volume 12, Issue 17 pp 17167—17208

SNAI1 is a prognostic biomarker and correlated with immune infiltrates in gastrointestinal cancers

Figure 4. Correlation of SNAI1 expression with immune cells in cancer. (A) The landscape of relationship between SNAI1 expression and TILs in different types of cancer(red is positive correlated and blue is negative correlated). (BR) SNAI1 expression was positively closely related with infiltrating levels of CD56bright, CD56dim, macrophage, mast, MDSC, neutrophil, NK, NKT, pDC, tcm_CD4, tcm_CD8, Tfh, Tgd, Th1, Treg in stomach cancer, and was negatively correlated with infiltrating levels of act_CD4, Imm_B in stomach cancer. (SU) Correlation of SNAI1 expression and immune subtypes (wound healing, IFN-gamma dominant, inflammatory, lymphocyte depleted, TGF-β dominant) in COAD (colon adenocarcinoma), READ (rectum adenocarcinoma), and STAD (stomach adenocarcinoma).