Research Paper Volume 12, Issue 17 pp 17209—17223

CircRNA circ_0072995 promotes the progression of epithelial ovarian cancer by modulating miR-147a/CDK6 axis

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Figure 4. Overexpression of miR-147a inhibited EOC cell proliferation and migration, induced apoptosis in vitro. (A) Transfection efficiency of miR-147a mimics was determined by qRT-PCR. (B) The effect of miR-147a and miR-147a mimics on EOC cell growth curves was detected by CCK-8 assays. (C, D) The effect of miR-147a and miR-147a mimics on EOC cell migratory and invasive capabilities was detected by wound healing and transwell assays. (E) The effect of miR-147a and miR-147a mimics on EOC cell apoptosis was detected by flow cytometry apoptosis.