Research Paper Volume 12, Issue 18 pp 18238—18250

The mitochondrial-targeted peptide SBT-20 ameliorates inflammation and oxidative stress in chronic renal failure

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Figure 4.

SBT-20 protect mitochondria protection in vivo. (A) Transmission electron microscope image of mitochondria in outer medulla. (B) Representative image of Immunohistochemistry (IHC). (C) The protein expression of Drp1 and Mfn2 in renal tissues. n=5. (*P<0.05 vs. sham group, #P<0.05 vs. CRF group).