Research Paper Volume 12, Issue 18 pp 18238—18250
The mitochondrial-targeted peptide SBT-20 ameliorates inflammation and oxidative stress in chronic renal failure
Figure 5. SBT-20 prevents inflammation in CRF mice. (A) Macrophage infiltration in different group. (B) The mRNA level of inflammatory cytokines (IL-1β, IL-6, NF-κB1 and NF-κB2). n=5. (C) The protein expression of NF-κB-p65 and TNFα in renal tissues. n=5. (*P<0.05 vs. sham group, #P<0.05 vs. CRF group).