Research Paper Volume 12, Issue 17 pp 17288—17294

Male patients with TERT mutation may be more likely to benefit from immunotherapy, especially for melanoma

Figure 2. The effect of TERT mutation and sex disparity on the efficacy of immunotherapy in cBioPortal database. (A) Kaplan-Meier survival analysis between female and male patients in ICI treatment cohort. The red curve represents female group, and the blue curve represents male group. (B) Kaplan-Meier survival analysis between TERT altered and unaltered group in ICI treatment cohort. The red curve represents TERT altered group, and the blue curve represents unaltered group. (C) Kaplan-Meier survival analysis between TERT altered and unaltered group in the TERT-male cohort. The red curve represents TERT altered group, and the blue curve represents unaltered group. (D) Kaplan-Meier survival analysis between TERT altered and unaltered group in the TERT-female cohort. The red curve represents TERT altered group, and the blue curve represents unaltered group.