Research Paper Volume 12, Issue 17 pp 17288—17294

Male patients with TERT mutation may be more likely to benefit from immunotherapy, especially for melanoma

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Figure 2. The effect of TERT mutation and sex disparity on the efficacy of immunotherapy in cBioPortal database. (A) Kaplan-Meier survival analysis between female and male patients in ICI treatment cohort. The red curve represents female group, and the blue curve represents male group. (B) Kaplan-Meier survival analysis between TERT altered and unaltered group in ICI treatment cohort. The red curve represents TERT altered group, and the blue curve represents unaltered group. (C) Kaplan-Meier survival analysis between TERT altered and unaltered group in the TERT-male cohort. The red curve represents TERT altered group, and the blue curve represents unaltered group. (D) Kaplan-Meier survival analysis between TERT altered and unaltered group in the TERT-female cohort. The red curve represents TERT altered group, and the blue curve represents unaltered group.