Research Paper Volume 12, Issue 16 pp 16368—16389

Flavonoids from Rosa roxburghii Tratt prevent reactive oxygen species-mediated DNA damage in thymus cells both combined with and without PARP-1 expression after exposure to radiation in vivo

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Figure 7.

FRT protected against radiation damage by regulating the PARP-1/ROS/DNA pathway, and by inhibiting the activation of PARP-1/AIF.