Research Paper Volume 13, Issue 6 pp 9119—9134

Silencing of circular RNA_0000326 inhibits cervical cancer cell proliferation, migration and invasion by boosting microRNA-338-3p-dependent down-regulation of CDK4


Figure 1. Circ_0000326 is upregulated in cervical cancer. (A) Circ_0000326 expression in cervical cancer analyzed through GSE102686 (circRNA_000543 circBase stands for circ_0000326). (B) Circ_0000326 expression in 60 paired cervical cancer tissues and adjacent normal tissues determined by RT-qPCR. (C) Correlation between circ_0000326 expression and T classifications (T1-T4) in 60 cases of cervical cancer tissues. * p < 0.05 vs. normal tissues. Data were expressed as mean ± standard deviation and analyzed by paired t test. n = 60.