Research Paper Volume 12, Issue 16 pp 16457—16475

Risk stratification of cutaneous melanoma reveals carcinogen metabolism enrichment and immune inhibition in high-risk patients


Figure 2.

Comparison of the 21-gene signature with known biomarkers in predicting the OS in the TCGA cohort. Kaplan–Meier analysis was performed for patients classified by the 31-gene (A), 53-gene (B), and methylation (C) signatures. (D) ROC curves of the three known signatures and the 21-gene signature are shown. The AUC values of each signature demonstrate their ability to predict the patient OS.