Research Paper Volume 12, Issue 17 pp 17528—17540
Two identified subsets of CD8 T cells in obstructed kidneys play different roles in inflammation and fibrosis
Figure 5. Tc2-treated macrophages promoted the differentiation of fibroblasts to myofibroblasts more than Tc1. (A–C) NIH3T3 cells cocultured with Raw264.7 cells, Tc1 plus Raw264.7 cells, or Tc2 plus Raw264.7 cells were collected through cell sorting for mRNA examination (*p < 0.05 vs. Raw264.7 cells + NIH3T3 cells, #p < 0.05 vs. Tc1 + Raw264.7 cells + NIH3T3 cells). (D) NIH3T3 cells were cocultured for 24 and 48 h with Raw264.7 cells plus Tc1 or Tc2 to assay cell contraction assay by using a cell contraction assay kit. Changes in gel size were indicated by red circles.