Research Paper Volume 12, Issue 17 pp 17568—17581

HSPB8 overexpression prevents disruption of blood-brain barrier after intracerebral hemorrhage in rats through Akt/GSK3β/β-catenin signaling pathway

Figure 4. HSPB8 overexpression inhibited ICH-induced BBB destruction. (A) Quantitative analysis of Evans blue extravasation at 24h after ICH (n=5, mean±SEM). (B) TEM images of the morphometric changes of BBB (n=5, mean±SEM). EC: endothelial cell; L: lumina. Arrowheads show TJ. **P <0 .01 versus indicated group; *P <0.05 versus indicated group. n=number of animals per group.