Research Paper Volume 12, Issue 17 pp 17568—17581

HSPB8 overexpression prevents disruption of blood-brain barrier after intracerebral hemorrhage in rats through Akt/GSK3β/β-catenin signaling pathway

Figure 6. HSPB8 overexpression protected against ICH-induced TJPs degradation. (A) Occludin and claudin-5 expressions were measured by western blot. (B, C) Quantification of occludin and claudin-5 (n=5, mean ± SEM). (D, E) Representative images of occludin and claudin-5 positive vessels. Scale bar=50 μm (n=5, mean± SEM). **P <0.01 versus indicated group. n=number of animals per group.