Research Paper Volume 12, Issue 17 pp 17568—17581

HSPB8 overexpression prevents disruption of blood-brain barrier after intracerebral hemorrhage in rats through Akt/GSK3β/β-catenin signaling pathway

Figure 9. MK2206 attenuated the protective effects of HSPB8. (AC) Modified Garcia test, corner turn test, and limb placement test in sham, ICH+pLV-GFP, ICH+pLV-HSPB8, ICH+pLV-HSPB8+DMSO, ICH+pLV-HSPB8 + MK2206 groups (n=6, mean±SEM). (D) Evans blue dye extravasation in different groups (n=6, mean±SEM) *P <0.05 versus indicated group; **P <0.01 versus indicated group. n=number of animals per group.