Research Paper Volume 12, Issue 16 pp 16514—16538

Coupled immune stratification and identification of therapeutic candidates in patients with lung adenocarcinoma

Figure 4. Kaplan–Meier curves and mutation status of the four immune subtypes. (A) Overall survival (OS) of the four subtypes (log-rank test). (B) Five-year Kaplan–Meier curves for OS of subtypes C3 and C4 (log-rank test). (C) Distribution of EGFR, KRAS and ALK mutant among the four subtypes. The lower half represents the number of EGFR/KRAS mutant and wild-type of different subtypes (chi-square test). (D) Distribution of the number of mutant genes in the four samples (Analysis of Variance, p<0. 0001).