Research Paper Volume 12, Issue 17 pp 17681—17693

Long non-coding RNA Loc490 inhibits gastric cancer cell proliferation and metastasis by upregulating RNA-binding protein Quaking

Figure 3. Low expression of Loc490 confers GC cell proliferative advantage. (A). Expression of Loc490 in a normal gastric epithelial cell line and GC cell lines; (B, C) Overexpression/knockdown of Loc490 in GC cell lines; (D, H) Clone formation results in Loc490-overexpressing/knockdown cell lines; (E, I) MTS assay results; (F, J) Invasion assay results and quantification; (G, K) Migration assay results and quantification. Scale bars: 100 μm. Data represent the mean and SD from three experiments. *p < 0.05, **p < 0.01, ***p < 0.001.