Research Paper Volume 12, Issue 17 pp 17681—17693

Long non-coding RNA Loc490 inhibits gastric cancer cell proliferation and metastasis by upregulating RNA-binding protein Quaking

Figure 4. The expression of Loc490 changes the expression of EMT-related proteins. (A, C) Changes in QKI, N-cadherin, E-cadherin, MMP-9 and Vimentin mRNA levels in Loc490-overexpressing cell lines; (B) Changes in QKI, N-cadherin, E-cadherin, MMP-9 and Vimentin protein levels in Loc490-overexpressing cell lines; (D) Changes in QKI, N-cadherin, E-cadherin, MMP-9 and Vimentin protein levels in Loc490-knockdown cell lines; (E) RNA immunoprecipitation assay to detect Loc490 expression. Data represent the mean and SD from three experiments. *p < 0.05, **p < 0.01.