Figure 3. Knockdown of TRIB3 impairs the proliferation and migration of GBM cells. (A) The effect of TRIB3 knockdown on U251 and U87 cell proliferation was detected by CCK-8 assay at the indicated times. (B) The colony formation of U251 and U87 cells treated with si-NC and si-TRIB3. (C) Migration ability, and invasion ability were determined after the downregulation of TRIB3 in glioma cell lines using a migration assay and a Transwell assay. (D) The migration potential of U251 and U87 cells treated with si-NC and si-TRIB3 was evaluated by the wound healing test. *p<0.05, **p< 0.01.