COVID-19 Review Volume 12, Issue 18 pp 18778—18789

SARS-CoV-2, immunosenescence and inflammaging: partners in the COVID-19 crime

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Figure 2.

Immunosencescence and inflammaging create a vicious cycle creating an environment favorable for the development of neurodegenerative diseases. Such a relationship between these processes is mainly characteristic of the elderly and is the most likely reason for the increased incidence and adversity of COVID-19 among the elderly.