Research Paper Volume 12, Issue 24 pp 25172—25188

Vascular endothelial growth factor receptor-2 and its association with tumor immune regulatory gene expression in hepatocellular carcinoma

Figure 4. Expression levels of important checkpoint molecules including PD-1 (A), PD-L1 (B), CTLA-4 (C), IDO1 (D), and LAG3 (E) were all significantly higher in the high VEGF score subtype. Significantly lower TMB (F), SNV neoantigen number (G), and indel neoantigen number (H) were observed in the high VEGF score subtype.