Research Paper Volume 12, Issue 24 pp 25395—25411

Steroid 5 alpha-reductase 3 (SRD5A3) promotes tumor growth and predicts poor survival of human hepatocellular carcinoma (HCC)

Figure 9. Potential molecular mechanisms behind the effects of SRD5A3. (A, B) Protein-protein interaction network between SRD5A3 and other protein-coding genes from the GeneMANIA and STRING databases. (C) Upstream microRNA of SRD5A3 from the miRNACancerMAP web-portal. (D) Methylation level of SRD5A3 from the UALCAN web portal. (EL) Correlation analysis between CDK5, CDK4, CDK7, CDKAL1, CCNB1, CDK1, PLK1, AR and SRD5A3 in the GEPIA2 website portal. R, correlation coefficient.