Research Paper Volume 13, Issue 1 pp 340—350

LINC00052 ameliorates acute kidney injury by sponging miR-532-3p and activating the Wnt signaling pathway

The impacts of LINC00520 and miR-532-3p on inflammation and ROS levels in NRK-52E cells experiencing hypoxia. Expression of TNF-α (A), IL-1β (B) and IL-6 (C) mRNAs in NRK-52E cells infected with a combination of LV-LINC00052 and LV-miR-532-3p or LV-LINC00052 and LV-miR-532-3p was tested using q-RT-PCR. The levels of ROS (D), MDA (E), and SOD (F) under different conditions. Three independent experiments were performed. Error bars represent the mean ± SD of triplicate experiments (at least). *p

Figure 5. The impacts of LINC00520 and miR-532-3p on inflammation and ROS levels in NRK-52E cells experiencing hypoxia. Expression of TNF-α (A), IL-1β (B) and IL-6 (C) mRNAs in NRK-52E cells infected with a combination of LV-LINC00052 and LV-miR-532-3p or LV-LINC00052 and LV-miR-532-3p was tested using q-RT-PCR. The levels of ROS (D), MDA (E), and SOD (F) under different conditions. Three independent experiments were performed. Error bars represent the mean ± SD of triplicate experiments (at least). *p < 0.05.