Research Paper Volume 13, Issue 1 pp 340—350

LINC00052 ameliorates acute kidney injury by sponging miR-532-3p and activating the Wnt signaling pathway

miR-532-3p abolishes the repressive effect of LINC00520 by inactivation of the Wnt/β-catenin pathway in NRK-52E cells. (A) IHC staining of c-myc and cyclin D1 in AKI rat models. (B) Expression of β-catenin, c-myc, and cyclin D1 proteins in NRK-52E cells infected with a combination of LV-LINC00052 and LV-miR-532-3p or LV-LINC00052 and LV-miR-532-3p. Three independent experiments were performed. Error bars represent the mean ± SD of triplicate experiments (at least). *p

Figure 6. miR-532-3p abolishes the repressive effect of LINC00520 by inactivation of the Wnt/β-catenin pathway in NRK-52E cells. (A) IHC staining of c-myc and cyclin D1 in AKI rat models. (B) Expression of β-catenin, c-myc, and cyclin D1 proteins in NRK-52E cells infected with a combination of LV-LINC00052 and LV-miR-532-3p or LV-LINC00052 and LV-miR-532-3p. Three independent experiments were performed. Error bars represent the mean ± SD of triplicate experiments (at least). *p < 0.05.