Research Paper Volume 12, Issue 24 pp 25487—25504

Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits

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Figure 2.

Effects of PTX treatment on cognitive function in aged rats. (A) Effects of PTX treatment on the escape latency of aged rats. (B) Effects of PTX treatment on the number of platform crossings. (C) Effects of PTX treatment on time spent in the target quadrant. Data are expressed as the mean ± S.D. (n=6 rats/group). *P<0.05 versus 6Mon rats, **P<0.01 versus 6Mon rats, #P<0.05 versus 24Mon rats, ##P<0.01 versus 24Mon rats.