Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits

Yu Wang; Yunxiao Kang; Chunxiao Qi; Tianyun Zhang; Hui Zhao; Xiaoming Ji; Wensheng Yan; Yuanxiang Huang; Rui Cui; Guoliang Zhang; Geming Shi

doi:doi:10.18632/aging.104155

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Research Paper Volume 12, Issue 24 pp 25487—25504

Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits

Figure 5. Effects of PTX treatment on brain mitochondrial ATP levels and complex activity in aged rats. (A) ATP levels in the SN. (B) ATP levels in the HIPP. (C) Mitochondrial complex I activity in the SN. (D, E) Mitochondrial complex V activity in the SN and HIPP. Data are expressed as the mean ± S.D. (n=6 rats/group). *P<0.05, **P<0.01.