Research Paper Volume 12, Issue 24 pp 25487—25504
Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits
Figure 8. Effects of PTX treatment on mitochondrial biogenesis in the HIPP in aged rats. (A–C) PGC-1α, NRF-1, and TFAM mRNA levels were detected by qPCR. (D–F) Representative Western blots of PGC-1α, NRF-1, and TFAM protein levels. (G–I) PGC-1α, NRF-1, and TFAM protein levels were quantified relative to β-actin band density. Data are expressed as the mean ± S.D. (n=6 rats/group). *P<0.05, **P<0.01.