Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits

Yu Wang; Yunxiao Kang; Chunxiao Qi; Tianyun Zhang; Hui Zhao; Xiaoming Ji; Wensheng Yan; Yuanxiang Huang; Rui Cui; Guoliang Zhang; Geming Shi

doi:doi:10.18632/aging.104155

← Back

Research Paper Volume 12, Issue 24 pp 25487—25504

Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits

Figure 9. Effects of PTX treatment on mitochondrial content in the aged rat brain. (A, B) CS activity in the SN and HIPP. (C, D) mtDNA copy number in the SN and HIPP. (E, F) ATP6 mRNA levels in the SN and HIPP. Data are expressed as the mean ± S.D. (n=6 rats/group). *P<0.05, **P<0.01.