Research Paper Volume 12, Issue 24 pp 25643—25657

Neurofilament degradation is involved in laparotomy-induced cognitive dysfunction in aged rats

Figure 6. KEGG pathway analysis in the surgery + TSA group vs. the surgery group at 6 h post-surgery. (A) Top nine significantly enriched pathways identified by KEGG analysis. (B) Pathway enrichment analysis of differential expression of proteins. (C, D) Results show proteins involved in the focal eadhesion and ECM-receptor interaction pathways. Red colors represent the proteins that are upregulated, and blue colors represent the proteins that are downregulated.