Research Paper Volume 13, Issue 3 pp 3342—3352

The DNA methylation-regulated MCTP1 activates the drug-resistance of esophageal cancer cells

Drug resistance profiling of ten esophageal cancer cell lines. (A) Experimental scheme. (B–E) IC50 values of the four indicated chemotherapeutics. for ten esophageal cancer cell lines. The cell survival rates were calculated as percentages relative to the mock treatment and plotted against lg μg/ml of drug. (F) The IC50 values to those of the most sensitive cell cine (Kyse450) are presented in the table.

Figure 1. Drug resistance profiling of ten esophageal cancer cell lines. (A) Experimental scheme. (BE) IC50 values of the four indicated chemotherapeutics. for ten esophageal cancer cell lines. The cell survival rates were calculated as percentages relative to the mock treatment and plotted against lg μg/ml of drug. (F) The IC50 values to those of the most sensitive cell cine (Kyse450) are presented in the table.