Research Paper Volume 12, Issue 24 pp 25684—25699

A SNP involved in alternative splicing of ABCB1 is associated with clopidogrel resistance in coronary heart disease in Chinese population


Figure 4. Human Splicing Finder version 3.1 (HSF) and ESE finder 3.0 bioinformatics analysis softwares are used to predict the effect the mutation of the rs1045642 SNP of the ABCB1 gene on AS. (A) The three algorithms of HSF software predict that polymorphism is an ESE site. (B) ESE finder software predicts the binding ability of ESE site to SRps.