Research Paper Volume 12, Issue 24 pp 25730—25743

Cardamonin induces G2/M phase arrest and apoptosis through inhibition of NF-κB and mTOR pathways in ovarian cancer

Figure 1. Cardamonin inhibits SKOV3 ovarian cancer cell growth. (A) Chemical structure of the active form of (E)-1-(2,4-dihydroxy-6-methoxypheny)-3-phenylprop-2-en-1-one (cardamonin). (B) Image showing H&E staining of original tumor dissected from patient. (C, D) Graph showing the inhibitory effects of cardamonin on proliferation of SKOV3 and PDC cells. Average results from three independent experiments are presented; SD signifies standard deviation (n=3).