Research Paper Volume 12, Issue 24 pp 25865—25877

Downregulation of enhancer RNA EMX2OS is associated with poor prognosis in kidney renal clear cell carcinoma

Figure 1. Association between EMX2OS expression and the key clinicopathological characteristics of KIRC. (A) EMX2OS expression was significantly lower in KIRC tissue samples than in normal tissue samples. (B) EMX2OS downregulation was significantly correlated with poorer overall survival in KIRC. (C) EMX2 downregulation was significantly correlated with poorer overall survival in KIRC. (D) Correlation analysis between EMX2OS and its predicted target EMX2. (E) EMX2OS expression significantly decreased with increasing histological grade. (F) EMX2OS expression significantly decreased with increasing tumor size (T stage). (G) EMX2OS expression significantly decreased with advanced AJCC stages. (H) EMX2OS expression in pan-cancer from TIMER database (https://cistrome.shinyapps.io/timer/). KIRC, kidney renal clear cell carcinoma; AJCC, American Joint Committee on Cancer.