Research Paper Volume 12, Issue 24 pp 25878—25894

Upregulation of KIF20A promotes tumor proliferation and invasion in renal clear cell carcinoma and is associated with adverse clinical outcome

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Figure 4. Identification of modules associated with the KIF20A expression in the TCGA-KIRC dataset. (A) The Cluster dendrogram of co-expression network modules were ordered by a hierarchical clustering of genes based on the 1-TOM matrix. Each module was assigned to different colors; (B) Module-trait relationships. Each row corresponds to a color module and column corresponds to a clinical trait. Each cell contains the corresponding correlation and P-value; (C) The pink module (the corresponding correlation and P-value); (D) Edges and nodes in pink module; (E) Top 10 nodes in PPI network; (F) GO analysis of module genes; (G) KEGG analysis of module genes. Abbreviations: PPI: Protein-protein interaction; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes.