Research Paper Volume 12, Issue 24 pp 25878—25894

Upregulation of KIF20A promotes tumor proliferation and invasion in renal clear cell carcinoma and is associated with adverse clinical outcome

Figure 4. Identification of modules associated with the KIF20A expression in the TCGA-KIRC dataset. (A) The Cluster dendrogram of co-expression network modules were ordered by a hierarchical clustering of genes based on the 1-TOM matrix. Each module was assigned to different colors; (B) Module-trait relationships. Each row corresponds to a color module and column corresponds to a clinical trait. Each cell contains the corresponding correlation and P-value; (C) The pink module (the corresponding correlation and P-value); (D) Edges and nodes in pink module; (E) Top 10 nodes in PPI network; (F) GO analysis of module genes; (G) KEGG analysis of module genes. Abbreviations: PPI: Protein-protein interaction; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes.