Research Paper Volume 12, Issue 24 pp 25939—25955

Sexual dimorphism in aging hematopoiesis: an earlier decline of hematopoietic stem and progenitor cells in male than female mice

Figure 5. Comparisons of relative pituitary SexHR gene expression between male and female of young, middle-aged and old mice. Total RNA was purified from LSKs of indicated mice and subjected to real-time PCR to detect gene expression. GAPDH was used as a reference gene to normalize each gene expression. Left panels: FSHR gene expression between male and female of young, middle-aged and old mice. Middle panels: LHR gene expression between male and female of young, middle-aged and old mice. Right panels: PRLR gene expression between male and female of young, middle-aged and old mice. FSHR: follicle-stimulating hormone receptor, LHR: luteinizing hormone receptor, PRLR: prolactin receptor. * P < 0.05, ** P < 0.01.